論文

原著論文と総説

〇[Title] Advanced Diagnostic System and Introduction of Newborn Screening of Adrenoleukodystrophy and Peroxisomal Disorders in Japan.

Nobuyuki Shimozawa, Shigeo Takashima, Hiroki Kawai, Kazuo Kubota, Hideo Sasai, Kenji Orii, Megumi Ogawa, Hidenori Ohnishi

International journal of neonatal screening 7(3) Aug 25, 2021

〇[Title] The new live imagers MitoMM1/2 for mitochondrial visualization.

Miwa Maeda, Mayu Suzuki, Shigeo Takashima, Tsutomu Sasaki, Kentaro Oh-Hashi, Hiroshi Takemori

Biochemical and biophysical research communications 562 50-54 Jul 12, 2021

〇[Title] Zebrafish model of human Zellweger syndrome reveals organ-specific accumulation of distinct fatty acid species and widespread gene expression changes.

Shigeo Takashima, Shoko Takemoto, Kayoko Toyoshi, Akiko Ohba, Nobuyuki Shimozawa

Molecular genetics and metabolism 133(3) 307-323 Jul, 2021

〇[Title] Recombinant antithrombin attenuates acute respiratory distress syndrome in experimental endotoxemia.

Haruka Okamoto, Isamu Muraki, Hideshi Okada, Hiroyuki Tomita, Kodai Suzuki, Chihiro Takada, Yugo Wakayama, Ayumi Kuroda, Hirotsugu Fukuda, Yuki Kawasaki, Ayane Nishio, Maho Matsuo, Yuto Tamaoki, Risa Inagawa, Shigeo Takashima, Toshiaki Taniguchi, Akio Suzuki, Keiko Suzuki, Nagisa Miyazaki, Yoshinori Kakino, Ryu Yasuda, Tetsuya Fukuta, Yuichiro Kitagawa, Takahito Miyake, Tomoaki Doi, Takahiro Yoshida, Shozo Yoshida, Shinji Ogura

The American journal of pathology  Jun 8, 2021

〇[Title] Fatty acid composition of the methylotrophic yeast Komagataella phaffii grown under low- and high-methanol conditions.

Pengli Ma, Shigeo Takashima, Chikako Fujita, Saya Yamada, Yusuke Oshima, Hao-Liang Cai, Hiroya Yurimoto, Yasuyoshi Sakai, Takashi Hayakawa, Masaya Shimada, Xia Ning, Baoyao Wei, Tomoyuki Nakagawa

Yeast (Chichester, England)  Jun 5, 2021

〇[Title] Clinical evaluation of childhood cerebral adrenoleukodystrophy with balint's symptoms.

Kazuo Kubota, Hiroki Kawai, Shigeo Takashima, Takayoshi Shimohata, Mika Otsuki, Hidenori Ohnishi, Nobuyuki Shimozawa

Brain & development 43(3) 396-401 Mar, 2021

〇[Title] Proteomic profiling of milk small extracellular vesicles from bovine leukemia virus-infected cattle.

Md Matiur Rahman, Shigeo Takashima, Yuji O Kamatari, Yassien Badr, Yuko Kitamura, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima

Scientific reports 11(1) 2951-2951 Feb 3, 2021

〇[Title] Glucose transporter Glut1 controls diffuse invasion phenotype with perineuronal satellitosis in diffuse glioma microenvironment

Masafumi Miyai, Tomohiro Kanayama, Fuminori Hyodo, Takamasa Kinoshita, Takuma Ishihara, Hideshi Okada, Hiroki Suzuki, Shigeo Takashima, Zhiliang Wu, Yuichiro Hatano, Yusuke Egashira, Yukiko Enomoto, Noriyuki Nakayama, Akio Soeda, Hirohito Yano, Akihiro Hirata, Masayuki Niwa, Shigeyuki Sugie, Takashi Mori, Yoichi Maekawa, Toru Iwama, Masayuki Matsuo, Akira Hara, Hiroyuki Tomita

Neuro-Oncology Advances 3(1) Jan 1, 2021

〇[Title] Changes in the gene expression in mouse astrocytes induced by pulsed radiofrequency: A preliminary study.

Kumiko Tanabe, Shigeo Takashima, Hiroki Iida

Neuroscience letters  135536-135536 Nov 28, 2020

〇[Title] Novel ACOX1 mutations in two siblings with peroxisomal acyl-CoA oxidase deficiency.

Atsushi Morita, Takashi Enokizono, Tatsuyuki Ohto, Mai Tanaka, Shiena Watanabe, Yui Takada, Kazuhiro Iwama, Takeshi Mizuguchi, Naomichi Matsumoto, Masashi Morita, Shigeo Takashima, Nobuyuki Shimozawa, Hidetoshi Takada

Brain & development 43(3) 475-481 Nov 21, 2020

〇[Title] Positional determination of the carbon-carbon double bonds in unsaturated fatty acids mediated by solvent plasmatization using LC-MS.

[Author]  Shigeo Takashima,Kayoko Toyoshi,Takuhei Yamamoto,Nobuyuki Shimozawa

Scientific reports 10(1) 12988-12988 7 31, 2020

〇[Title] mRNA Profile in Milk Extracellular Vesicles from Bovine Leukemia Virus-Infected Cattle.

[Author] Hinata Ishikawa,Md Matiur Rahman,Marika Yamauchi, Shigeo Takashima,Yoshiko Wakihara,Yuji O Kamatari,Kaori Shimizu,Ayaka Okada,Yasuo Inoshima

Viruses 12(6) 6 20, 2020

〇[Title] Recombinant Thrombomodulin Protects Against Lipopolysaccharide-induced Acute Respiratory Distress Syndrome Via Preservation of Pulmonary Endothelial Glycocalyx.

[Author] Kodai Suzuki,Hideshi Okada,Genzou Takemura,Chihiro Takada,Hiroyuki Tomita,Hirohisa Yano,Isamu Muraki,Ryogen Zaikokuji,Ayumi Kuroda,Hirotsugu Fukuda,Ayane Nishio, Shigeo Takashima,Akio Suzuki,Nagisa Miyazaki,Tetsuya Fukuta,Noriaki Yamada,Takatomo Watanabe,Tomoaki Doi,Takahiro Yoshida,Keisuke Kumada,Hiroaki Ushikoshi,Shozo Yoshida,Shinji Ogura

British journal of pharmacology  6 4, 2020

〇[Title] Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells.

[Author] Kotaro Hama,Yuko Fujiwara, Shigeo Takashima,Yasuhiro Hayashi,Atsushi Yamashita,Nobuyuki Shimozawa,Kazuaki Yokoyama

Journal of lipid research 61(4) 523-536 4 2020

〇[Title] The High Content of Ent-11α-hydroxy-15-oxo-kaur- 16-en-19-oic Acid in Adenostemma lavenia (L.) O. Kuntze Leaf Extract: With Preliminary in Vivo Assays.

[Author] Akie Hamamoto,Ryosuke Isogai,Miwa Maeda,Masumi Hayazaki,Eito Horiyama, Shigeo Takashima,Mamoru Koketsu,Hiroshi Takemori

Foods (Basel, Switzerland) 9(1) 1 9, 2020

〇[Title] Sexual precocity in male microminipigs evaluated immunohistologically using spermatogonial stem cell markers.

[Author] Julio Almunia,Kotono Nakamura,Mami Murakami, Shigeo Takashima,Takashi Mori,Masaki Takasu

Theriogenology 130 120-124 5 2019

〇[Title] Treatment with myo-inositol attenuates binding of the carbohydrate-responsive element-binding protein to the ChREBP-β and FASN genes in rat nonalcoholic fatty liver induced by high-fructose diet.

[Author] Masaya Shimada,Yutaro Ichigo,Bungo Shirouchi, Shigeo Takashima,Mizuho Inagaki,Tomoyuki Nakagawa,Takashi Hayakawa

Nutrition research (New York, N.Y.) 64 49-55 4 2019

〇[Title] Expanding the concept of peroxisomal diseases and efficient diagnostic system in Japan.

[Author]  Shigeo Takashima,Hirotomo Saitsu,Nobuyuki Shimozawa

Journal of human genetics 64(2) 145-152 2 2019 (総説)

〇[Title] Atypical PEX16 peroxisome biogenesis disorder with mild biochemical disruptions and long survival.

[Author] Nuha Al Zaabi,Anoud Kendi,Fatma Al-Jasmi, Shigeo Takashima,Nobuyuki Shimozawa,Osama Y Al-Dirbashi

Brain & development 41(1) 57-65 1 2019

〇[Title] Analyses of the fatty acid separation principle using liquid chromatography-mass spectrometry

[Author] Shigeo Takashima, Kayoko Toyoshi, Nobuyuki Shimozawa

Medical Mass Spectrometry 2(1) 6 2018

〇[Title] Characterization of domestic pig spermatogenesis using spermatogonial stem cell markers in the early months of life.

[Author] Julio Almunia,Kotono Nakamura,Mami Murakami, Shigeo Takashima,Masaki Takasu

Theriogenology 107 154-161 2 2018

〇[Title] Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice.

[Author] Kotaro Hama,Yuko Fujiwara,Masashi Morita,Fumiyoshi Yamazaki,Yuko Nakashima,Shiro Takei, Shigeo Takashima,Mitsutoshi Setou,Nobuyuki Shimozawa,Tsuneo Imanaka,Kazuaki Yokoyama

Lipids 53(1) 85-102 1 2018

〇[Title] Mitochondrial dynamics regulates Drosophila intestinal stem cell differentiation.

[Author] Hansong Deng*, Shigeo Takashima*, Manash Paul, Ming Guo, Volker Hartenstein (*Co-first authors)

Cell death discovery 4 17-17 2018

〇[Title] Effect of Lorenzo's Oil on Hepatic Gene Expression and the Serum Fatty Acid Level in abcd1-Deficient Mice.

[Author] Masashi Morita,Ayako Honda,Akira Kobayashi,Yuichi Watanabe,Shiro Watanabe,Kosuke Kawaguchi, Shigeo Takashima,Nobuyuki Shimozawa,Tsuneo Imanaka

JIMD reports 38 67-74 2018

〇[Title] bHLH proneural genes as cell fate determinants of entero-endocrine cells, an evolutionarily conserved lineage sharing a common root with sensory neurons.

[Author] Volker Hartenstein, Shigeo Takashima,Parvana Hartenstein,Samuel Asanad,Kian Asanad

Developmental biology 431(1) 36-47 11 1, 2017

〇[Title] Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling.

[Author] Mitsuyoshi Tanishima, Shigeo Takashima,Arata Honda,Daisuke Yasuda,Takashi Tanikawa,Satoshi Ishii,Takashi MaruYama

The Journal of biological chemistry 292(42) 17250-17257 10 20, 2017

〇[Title] Ataxic form of autosomal recessive PEX10-related peroxisome biogenesis disorders with a novel compound heterozygous gene mutation and characteristic clinical phenotype.

[Author] Toru Yamashita,Jun Mitsui,Nobuyuki Shimozawa, Shigeo Takashima,Hiroshi Umemura,Kota Sato,Mami Takemoto,Nozomi Hishikawa,Yasuyuki Ohta,Takashi Matsukawa,Hiroyuki Ishiura,Jun Yoshimura,Koichiro Doi,Shinichi Morishita,Shoji Tsuji,Koji Abe

Journal of the neurological sciences 375 424-429 4 15, 2017

〇[Title] Detection of unusual very-long-chain fatty acid and ether lipid derivatives in the fibroblasts and plasma of patients with peroxisomal diseases using liquid chromatography-mass spectrometry.

[Author]  Shigeo Takashima,Kayoko Toyoshi,Takahiro Itoh,Naomi Kajiwara,Ayako Honda,Akiko Ohba,Shoko Takemoto,Satoshi Yoshida,Nobuyuki Shimozawa

Molecular genetics and metabolism 120(3) 255-268 3 2017

〇[Title] A first case of adrenomyeloneuropathy with mutation Y174S of the adrenoleukodystrophy gene.

[Author] Yukio Horikawa,Mayumi Enya,Nobuaki Yoshikura,Junichi Kitagawa, Shigeo Takashima,Nobuyuki Shimozawa,Jun Takeda

Neuro endocrinology letters 38(1) 13-18 2 2017

〇[Title] Metamorphosis of the Drosophila visceral musculature and its role in intestinal morphogenesis and stem cell formation.

[Author] Patrick Aghajanian, Shigeo Takashima,Manash Paul,Amelia Younossi-Hartenstein,Volker Hartenstein

Developmental biology 420(1) 43-59 12 1, 2016

〇[Title] Origin and dynamic lineage characteristics of the developing Drosophila midgut stem cells.

[Author]  Shigeo Takashima,Patrick Aghajanian,Amelia Younossi-Hartenstein,Volker Hartenstein

Developmental biology 416(2) 347-60 8 15, 2016

〇[Title] Drosophila as a Model to Study Intestinal Stem Cells

[Author]  Shigeo Takashima

eLS, DOI: 10.1002/9780470015902.a0022526  11 2015 (総説)

〇[Title] Evaluation of SLC20A2 mutations that cause idiopathic basal ganglia calcification in Japan

[Author] Megumi Yamada,Masaki Tanaka,Mari Takagi,Seiju Kobayashi,Yoshiharu Taguchi,Shutaro Takashima,Kortaro Tanaka,Tetsuo Touge,Hiroyuki Hatsuta,Shigeo Murayama,Yuichi Hayashi,Masayuki Kaneko,Hiroyuki Ishiura,Jun Mitsui,Naoki Atsuta,Gen Sobue,Nobuyuki Shimozawa,Takashi Inuzuka,Shoji Tsuji,Isao Hozumi

NEUROLOGY 82(8) 705-712 2 2014

〇[Title] Migration of Drosophila intestinal stem cells across organ boundaries.

[Author]  Shigeo Takashima,Manash Paul,Patrick Aghajanian,Amelia Younossi-Hartenstein,Volker Hartenstein

Development (Cambridge, England) 140(9) 1903-11 5 2013

〇[Title] Stem cells and lineages of the intestine: a developmental and evolutionary perspective.

[Author]  Shigeo Takashima,David Gold,Volker Hartenstein

Development genes and evolution 223(1-2) 85-102 3 2013 (総説)

〇[Title] Dorsoventral patterning of the Drosophila hindgut is determined by interaction of genes under the control of two independent gene regulatory systems, the dorsal and terminal systems

[Author] Takashi Hamaguchi, Shigeo Takashima,Aiko Okamoto,Misa Imaoka, Takashi Okumura, Ryutaro Murakami

MECHANISMS OF DEVELOPMENT 129(9-12) 236-243 9 2012

〇[Title] Genetic control of intestinal stem cell specification and development: a comparative view.

[Author]  Shigeo Takashima,Volker Hartenstein

Stem cell reviews and reports 8(2) 597-608 6 2012 (総説)

〇[Title] Boule-like genes regulate male and female gametogenesis in the flatworm Macrostomum lignano.

[Author] Georg Kuales,Katrien De Mulder,Jade Glashauser,Willi Salvenmoser, Shigeo Takashima,Volker Hartenstein,Eugene Berezikov,Walter Salzburger,Peter Ladurner

Developmental biology 357(1) 117-32 9 1, 2011

〇[Title] A novel tissue in an established model system: the Drosophila pupal midgut.

[Author]  Shigeo Takashima,Amelia Younossi-Hartenstein,Paola A Ortiz,Volker Hartenstein

Development genes and evolution 221(2) 69-81 6 2011

〇[Title] Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway.

[Author]  Shigeo Takashima, Katrina L Adams, Paola A Ortiz, Chong T Ying, Rameen Moridzadeh, Amelia Younossi-Hartenstein, Volker Hartenstein

Developmental biology 353(2) 161-72 5 15, 2011

〇[Title] Conserved genetic pathways controlling the development of the diffuse endocrine system in vertebrates and Drosophila.

[Author] Volker Hartenstein, Shigeo Takashima, Katrina L Adams

General and comparative endocrinology 166(3) 462-9 5 1, 2010 (総説)

〇[Title] FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium.

[Author] Sachiko Tsuda,Tadao Kitagawa, Shigeo Takashima,Shuichi Asakawa,Nobuyoshi Shimizu,Hiroshi Mitani,Akihiro Shima,Makiko Tsutsumi,Hiroshi Hori,Kiyoshi Naruse,Yuji Ishikawa,Hiroyuki Takeda

Journal of cell science 123(Pt 3) 484-96 2 1, 2010

〇[Title] Drosophila cortex and neuropile glia influence secondary axon tract growth, pathfinding, and fasciculation in the developing larval brain.

[Author] Shana R Spindler,Irma Ortiz,Siaumin Fung, Shigeo Takashima,Volker Hartenstein

Developmental biology 334(2) 355-68 10 15, 2009

〇[Title] Characterization of teleost Mdga1 using a gene-trap approach in medaka (Oryzias latipes).

[Author] Shinya Sano, Shigeo Takashima,Hitomi Niwa,Hayato Yokoi,Atsuko Shimada,Alexander Arenz,Joachim Wittbrodt,Hiroyuki Takeda

Genesis (New York, N.Y. : 2000) 47(8) 505-13 8 2009

〇[Title] Phenotypic analyses of a medaka mutant reveal the importance of bilaterally synchronized expression of isthmic fgf8 for bilaterally symmetric formation of the optic tectum.

[Author]  Shigeo Takashima,Takahiro Kage,Takako Yasuda,Keiji Inohaya,Kouichi Maruyama,Kazuo Araki,Hiroyuki Takeda,Yuji Ishikawa

Genesis (New York, N.Y. : 2000) 46(10) 537-45 10 2008

〇[Title] The behaviour of Drosophila adult hindgut stem cells is controlled by Wnt and Hh signalling.

[Author]  Shigeo Takashima,Marianna Mkrtchyan,Amelia Younossi-Hartenstein,John R Merriam,Volker Hartenstein

Nature 454(7204) 651-5 7 31, 2008

〇[Title] Early development of the cerebellum in teleost fishes: a study based on gene expression patterns and histology in the medaka embryo.

[Author] Yuji Ishikawa,Takako Yasuda,Takahiro Kage, Shigeo Takashima,Masami Yoshimoto,Naoyuki Yamamoto,Kouichi Maruyama,Hiroyuki Takeda,Hironobu Ito

Zoological science 25(4) 407-18 4 2008

〇[Title] Phenotypic analysis of a novel chordin mutant in medaka.

[Author]  Shigeo Takashima,Atsuko Shimada,Daisuke Kobayashi,Hayato Yokoi,Takanori Narita,Tomoko Jindo,Takahiro Kage,Tadao Kitagawa,Tetsuaki Kimura,Koshin Sekimizu,Akimitsu Miyake,Davin H E Setiamarga,Ryohei Murakami,Sachiko Tsuda,Shinya Ooki,Ken Kakihara,Motoki Hojo,Kiyoshi Naruse,Hiroshi Mitani,Akihiro Shima,Yuji Ishikawa,Kazuo Araki,Yumiko Saga,Hiroyuki Takeda

Developmental dynamics : an official publication of the American Association of Anatomists 236(8) 2298-310 8 2007

〇[Title] Right-elevated expression of charon is regulated by fluid flow in medaka Kupffer's vesicle.

[Author] Motoki Hojo*, Shigeo Takashima* **,Daisuke Kobayashi,Akira Sumeragi,Atsuko Shimada,Tatsuya Tsukahara,Hayato Yokoi,Takanori Narita,Tomoko Jindo,Takahiro Kage,Tadao Kitagawa,Tetsuaki Kimura,Koshin Sekimizu,Akimitsu Miyake,Davin Setiamarga,Ryohei Murakami,Sachiko Tsuda,Shinya Ooki,Ken Kakihara,Kiyoshi Naruse,Hiroyuki Takeda** (*Co-first authors, **Co-corresponding authors)

Development, growth & differentiation 49(5) 395-405 6 2007

〇[Title] Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships.

[Author] Hayato Yokoi,Atsuko Shimada,Matthias Carl, Shigeo Takashima,Daisuke Kobayashi,Takanori Narita,Tomoko Jindo,Tetsuaki Kimura,Tadao Kitagawa,Takahiro Kage,Atsushi Sawada,Kiyoshi Naruse,Shuichi Asakawa,Nobuyoshi Shimizu,Hiroshi Mitani,Akihiro Shima,Makiko Tsutsumi,Hiroshi Hori,Joachim Wittbrodt,Yumiko Saga,Yuji Ishikawa,Kazuo Araki,Hiroyuki Takeda

Developmental biology 304(1) 326-37 4 1, 2007

〇[Title] Cell-fate choice and boundary formation by combined action of Notch and engrailed in the Drosophila hindgut.

[Author]  Shigeo Takashima,Haruka Yoshimori,Naoyuki Yamasaki,Kenji Matsuno,Ryutaro Murakami

Development genes and evolution 212(11) 534-41 12 2002

〇[Title] Regulation of pattern formation in the Drosophila hindgut by wg, hh, dpp, and en

[Author] Shigeo Takashima,Rutaro Murakami

MECHANISMS OF DEVELOPMENT 101(1-2) 79-90 3 2001

〇[Title] Developmental genetics of the Drosophila gut: Specification of primordia, subdivision and overt-differentiation

[Author] Ryutaro Murakami,Shigeo Takashima,Takashi Hamaguchi

CELLULAR AND MOLECULAR BIOLOGY 45(5) 661-676 7 1999 (総説)

その他出版物

実験医学（増刊）Vol. 28 No. 7
Author:Shigeo Takashima, Takashi Adachi
羊土社,  Role of cell death in adult intestinal tract, 2010/05
ISBN:978-4-7581-0306-0

細胞工学 Vol. 27 No. 11
Author:Shigeo Takashima, Volker Hartenstein
秀潤社, 2008/10
ISBN:978-4-87962-490-1